Eukaryotic gene expression is a tightly regulated process. While some genes are constitutive, many are turned on only in the presence of specific environmental cues within or outside the cell. This regulation ensures the timing and controls the rate by which gene products are produced when and where they are needed in the cell.

Gene regulation occurs at various levels. In this course, we will examine three aspects of eukaryotic gene regulation: [1] molecular mechanisms of regulation at transcription and post-transcription, [2] select signaling pathways that influence activation or repression of genes, and [3] impact of deregulated and/or misregulated gene expression pathways in cell function, growth, and differentiation.